Pseudoephedrine Hcl powder
Pseudoephedrine Hcl powder is one of the four active components of the herb Ephedra. It is able to induce fat loss via increasing the amount of fat available for fuel as well as by increasing heat expenditure. It has been implicated in increasing the metabolic rate by up to 5% in humans.
Pseudoephedrine Hcl powder is used for temporary relief of shortness of breath, chest tightness, and wheezing due to bronchial asthma. Ephedrine may also be used for other conditions as determined by your doctor.
Pseudoephedrine Hcl powder is a decongestant and bronchodilator. It works by reducing swelling and constricting blood vessels in the nasal passages and widening the lung airways, allowing you to breathe more easily.
Side effects of Pseudoephedrine Hcl powder
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most common side effects persist longer than one hours or become worse:
Dizziness; headache; nausea; nervousness; tremor; loss of appetite; restlessness; sleeplessness; stomach irritation.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating.
Pseudoephedrine Hcl is basically a synthetic version of ephedrine. Ephedra extract and ephedrine alkaloids (the latter of which is banned) are found naturally in plants, while ephedrine HCL is manufactured in a laboratory. Ephedrine HCL has a wide variety of medicinal uses. It’s often used as a bronchodilator to relieve symptoms of bronchial asthma which include shortness of breath, wheezing, coughing, and chest tightness. It has also been used to treat hypotension and nasal congestion with varying degrees of success.
How to take Pseudoephedrine Hcl
In an ECA stack, ephedrine is dosed at 20-24mg for three doses taken throughout the day.
Human studies have found success with ephedrine in isolation on fat metabolism with doses of 20-50mg thrice a day. The higher range (150mg) may be too stimulatory for some, and can induce headaches or light hand tremors.
Ephedrine tends to be consumed with xanthine compounds like caffeine and sometimes with Aspirin. The combination of Ephedrine and caffeine is shown repeatedly to be highly synergistic.
Mechanism of action
Pseudoephedrine, a sympathomimetic amine, acts on part of the sympathetic nervous system (SNS). The principal mechanism of action relies on its indirect stimulation of the adrenergic receptor system by increasing the activity of norepinephrine at the postsynaptic α and β receptors.The presence of direct interactions with α receptors is unlikely, but still controversial.L-ephedrine, and particularly its stereoisomer norpseudoephedrine (which is also present in Catha edulis) has indirect sympathomimetic effects and due to its ability to cross the blood-brain barrier, it is a CNS stimulant similar to amphetamines, but less pronounced, as it releases noradrenaline and dopamine in the substantia nigra.
The presence of an N-methyl group decreases binding affinities at α receptors, compared with norephedrine. Ephedrine, though, binds better than N-methylephedrine, which has an additional methyl group at the nitrogen atom. Also the steric orientation of the hydroxyl group is important for receptor binding and functional activity.